Birthweight and Childhood Cancer: Preliminary Findings from the International Childhood Cancer Cohort Consortium (I4C)
Identifieur interne : 003107 ( Main/Exploration ); précédent : 003106; suivant : 003108Birthweight and Childhood Cancer: Preliminary Findings from the International Childhood Cancer Cohort Consortium (I4C)
Auteurs : Ora Paltiel [Israël] ; Gabriella Tikellis [Australie] ; Martha Linet [Royaume-Uni] ; Jean Golding [Royaume-Uni] ; Stanley Lemeshow [Royaume-Uni] ; Gary Phillips [Royaume-Uni] ; Karen Lamb [Australie] ; Camilla Stoltenberg [Norvège] ; Siri E. H Berg [Norvège] ; Marin Str M [Danemark] ; Charlotta Granstr M [Danemark] ; Kate Northstone [Royaume-Uni] ; Mark Klebanoff [Royaume-Uni] ; Anne-Louise Ponsonby [Australie] ; Elizabeth Milne [Australie] ; Marie Pedersen [Espagne, France] ; Manolis Kogevinas [Espagne, Grèce] ; Eunhee Ha [Corée du Sud] ; Terence Dwyer [Australie, France]Source :
- Paediatric and Perinatal Epidemiology [ 0269-5022 ] ; 2015.
Descripteurs français
- KwdFr :
- Adolescent, Australie (épidémiologie), Danemark (épidémiologie), Enfant, Enfant d'âge préscolaire, Facteurs de risque, Femelle, Humains, Israël (épidémiologie), Mâle, Norvège (épidémiologie), Nourrisson, Nouveau-né, Odds ratio, Poids de naissance, Royaume-Uni (épidémiologie), Tumeurs (épidémiologie), Tumeurs (étiologie), Âge de début, États-Unis d'Amérique (épidémiologie).
- MESH :
- épidémiologie : Australie, Danemark, Israël, Norvège, Royaume-Uni, Tumeurs, États-Unis d'Amérique.
- étiologie : Tumeurs.
- Adolescent, Enfant, Enfant d'âge préscolaire, Facteurs de risque, Femelle, Humains, Mâle, Nourrisson, Nouveau-né, Odds ratio, Poids de naissance, Âge de début.
English descriptors
- KwdEn :
- Adolescent, Age of Onset, Australia (epidemiology), Birth Weight, Child, Child, Preschool, Denmark (epidemiology), Female, Humans, Infant, Infant, Newborn, Israel (epidemiology), Male, Neoplasms (epidemiology), Neoplasms (etiology), Norway (epidemiology), Odds Ratio, Risk Factors, United Kingdom (epidemiology), United States (epidemiology).
- MESH :
- epidemiology : Australia, Denmark, Israel, Neoplasms, Norway, United Kingdom, United States.
- etiology : Neoplasms.
- Adolescent, Age of Onset, Birth Weight, Child, Child, Preschool, Female, Humans, Infant, Infant, Newborn, Male, Odds Ratio, Risk Factors.
Abstract
Evidence relating childhood cancer to high birthweight is derived primarily from registry and case–control studies. We aimed to investigate this association, exploring the potential modifying roles of age at diagnosis and maternal anthropometrics, using prospectively collected data from the International Childhood Cancer Cohort Consortium.
We pooled data on infant and parental characteristics and cancer incidence from six geographically and temporally diverse member cohorts [the Avon Longitudinal Study of Parents and Children (UK), the Collaborative Perinatal Project (USA), the Danish National Birth Cohort (Denmark), the Jerusalem Perinatal Study (Israel), the Norwegian Mother and Child Cohort Study (Norway), and the Tasmanian Infant Health Survey (Australia)]. Birthweight metrics included a continuous measure, deciles, and categories (≥4.0 vs. <4.0 kilogram). Childhood cancer (377 cases diagnosed prior to age 15 years) risk was analysed by type (all sites, leukaemia, acute lymphoblastic leukaemia, and non-leukaemia) and age at diagnosis. We estimated hazard ratios (HR) and 95% confidence intervals (CI) from Cox proportional hazards models stratified by cohort.
A linear relationship was noted for each kilogram increment in birthweight adjusted for gender and gestational age for all cancers [HR = 1.26; 95% CI 1.02, 1.54]. Similar trends were observed for leukaemia. There were no significant interactions with maternal pre-pregnancy overweight or pregnancy weight gain. Birthweight ≥4.0 kg was associated with non-leukaemia cancer among children diagnosed at age ≥3 years [HR = 1.62; 95% CI 1.06, 2.46], but not at younger ages [HR = 0.7; 95% CI 0.45, 1.24,
Childhood cancer incidence rises with increasing birthweight. In older children, cancers other than leukaemia are particularly related to high birthweight. Maternal adiposity, currently widespread, was not demonstrated to substantially modify these associations. Common factors underlying foetal growth and carcinogenesis need to be further explored.
Url:
DOI: 10.1111/ppe.12193
PubMed: 25989709
PubMed Central: 4690513
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000377
- to stream Pmc, to step Curation: 000377
- to stream Pmc, to step Checkpoint: 001150
- to stream PubMed, to step Corpus: 002B64
- to stream PubMed, to step Curation: 002A92
- to stream PubMed, to step Checkpoint: 002A92
- to stream Ncbi, to step Merge: 002590
- to stream Ncbi, to step Curation: 002590
- to stream Ncbi, to step Checkpoint: 002590
- to stream Main, to step Merge: 003108
- to stream Main, to step Curation: 003107
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Birthweight and Childhood Cancer: Preliminary Findings from the International Childhood Cancer Cohort Consortium (I4C)</title><author><name sortKey="Paltiel, Ora" sort="Paltiel, Ora" uniqKey="Paltiel O" first="Ora" last="Paltiel">Ora Paltiel</name><affiliation wicri:level="1"><nlm:aff id="au1"><institution>Department of Hematology, Braun School of Public Health, Hadassah-Hebrew University</institution><addr-line>Jerusalem, Israel</addr-line></nlm:aff><country xml:lang="fr">Israël</country><wicri:regionArea>Jerusalem</wicri:regionArea></affiliation></author><author><name sortKey="Tikellis, Gabriella" sort="Tikellis, Gabriella" uniqKey="Tikellis G" first="Gabriella" last="Tikellis">Gabriella Tikellis</name><affiliation wicri:level="1"><nlm:aff id="au2"><institution>Department of Environmental and Genetic Epidemiology, Murdoch Children’s Research Institute, Royal Childrens Hospital, University of Melbourne</institution><addr-line>Melbourne, Australia</addr-line></nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Melbourne</wicri:regionArea></affiliation></author><author><name sortKey="Linet, Martha" sort="Linet, Martha" uniqKey="Linet M" first="Martha" last="Linet">Martha Linet</name><affiliation wicri:level="1"><nlm:aff id="au6"><institution>Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health</institution><addr-line>Bethesda, MD, UK</addr-line></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Bethesda, MD</wicri:regionArea><wicri:noRegion>MD</wicri:noRegion></affiliation></author><author><name sortKey="Golding, Jean" sort="Golding, Jean" uniqKey="Golding J" first="Jean" last="Golding">Jean Golding</name><affiliation wicri:level="1"><nlm:aff id="au10"><institution>Centre for Child & Adolescent Health, School of Social & Community Medicine, University of Bristol</institution><addr-line>Bristol, UK</addr-line></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Bristol</wicri:regionArea></affiliation></author><author><name sortKey="Lemeshow, Stanley" sort="Lemeshow, Stanley" uniqKey="Lemeshow S" first="Stanley" last="Lemeshow">Stanley Lemeshow</name><affiliation wicri:level="1"><nlm:aff id="au7"><institution>Division of Biostatistics, College of Public Health, The Ohio State University</institution><addr-line>Columbus, Ohio, UK</addr-line></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Columbus, Ohio</wicri:regionArea><wicri:noRegion>Ohio</wicri:noRegion></affiliation></author><author><name sortKey="Phillips, Gary" sort="Phillips, Gary" uniqKey="Phillips G" first="Gary" last="Phillips">Gary Phillips</name><affiliation wicri:level="1"><nlm:aff id="au8"><institution>Division of Biostatistics, The Ohio State University Center for Biostatistics</institution><addr-line>Columbus, Ohio, UK</addr-line></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Columbus, Ohio</wicri:regionArea><wicri:noRegion>Ohio</wicri:noRegion></affiliation></author><author><name sortKey="Lamb, Karen" sort="Lamb, Karen" uniqKey="Lamb K" first="Karen" last="Lamb">Karen Lamb</name><affiliation wicri:level="1"><nlm:aff id="au3"><institution>Centre for Physical Activity and Nutrition, Deakin University</institution><addr-line>Burwood, Australia</addr-line></nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Burwood</wicri:regionArea></affiliation></author><author><name sortKey="Stoltenberg, Camilla" sort="Stoltenberg, Camilla" uniqKey="Stoltenberg C" first="Camilla" last="Stoltenberg">Camilla Stoltenberg</name><affiliation wicri:level="1"><nlm:aff id="au12"><institution>Norwegian Institute of Public Health</institution><addr-line>Oslo, Norway</addr-line></nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea>Oslo</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="au13"><institution>Department of Global Public Health and Community Care, University of Bergen</institution><addr-line>Bergen, Norway</addr-line></nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea>Bergen</wicri:regionArea></affiliation></author><author><name sortKey="H Berg, Siri E" sort="H Berg, Siri E" uniqKey="H Berg S" first="Siri E" last="H Berg">Siri E. H Berg</name><affiliation wicri:level="1"><nlm:aff id="au12"><institution>Norwegian Institute of Public Health</institution><addr-line>Oslo, Norway</addr-line></nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea>Oslo</wicri:regionArea></affiliation></author><author><name sortKey="Str M, Marin" sort="Str M, Marin" uniqKey="Str M M" first="Marin" last="Str M">Marin Str M</name><affiliation wicri:level="1"><nlm:aff id="au14"><institution>Department of Epidemiology Research, Center for Fetal Programming, Statenserum Institute</institution><addr-line>Copenhagen, Denmark</addr-line></nlm:aff><country xml:lang="fr">Danemark</country><wicri:regionArea>Copenhagen</wicri:regionArea></affiliation></author><author><name sortKey="Granstr M, Charlotta" sort="Granstr M, Charlotta" uniqKey="Granstr M C" first="Charlotta" last="Granstr M">Charlotta Granstr M</name><affiliation wicri:level="1"><nlm:aff id="au14"><institution>Department of Epidemiology Research, Center for Fetal Programming, Statenserum Institute</institution><addr-line>Copenhagen, Denmark</addr-line></nlm:aff><country xml:lang="fr">Danemark</country><wicri:regionArea>Copenhagen</wicri:regionArea></affiliation></author><author><name sortKey="Northstone, Kate" sort="Northstone, Kate" uniqKey="Northstone K" first="Kate" last="Northstone">Kate Northstone</name><affiliation wicri:level="1"><nlm:aff id="au11"><institution>ALSPAC (Children of the 90s), School of Social and Community Medicine, University of Bristol</institution><addr-line>Bristol, UK</addr-line></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Bristol</wicri:regionArea></affiliation></author><author><name sortKey="Klebanoff, Mark" sort="Klebanoff, Mark" uniqKey="Klebanoff M" first="Mark" last="Klebanoff">Mark Klebanoff</name><affiliation wicri:level="1"><nlm:aff id="au7"><institution>Division of Biostatistics, College of Public Health, The Ohio State University</institution><addr-line>Columbus, Ohio, UK</addr-line></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Columbus, Ohio</wicri:regionArea><wicri:noRegion>Ohio</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="au9"><institution>The Research Institute at Nationwide Children’s Hospital, The Ohio State University College of Medicine</institution><addr-line>Columbus, OH, UK</addr-line></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Columbus, OH</wicri:regionArea><wicri:noRegion>OH</wicri:noRegion></affiliation></author><author><name sortKey="Ponsonby, Anne Louise" sort="Ponsonby, Anne Louise" uniqKey="Ponsonby A" first="Anne-Louise" last="Ponsonby">Anne-Louise Ponsonby</name><affiliation wicri:level="1"><nlm:aff id="au2"><institution>Department of Environmental and Genetic Epidemiology, Murdoch Children’s Research Institute, Royal Childrens Hospital, University of Melbourne</institution><addr-line>Melbourne, Australia</addr-line></nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Melbourne</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="au4"><institution>Menzies Research Institute, University of Tasmania</institution><addr-line>Hobart, Tasmania, Australia</addr-line></nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Hobart, Tasmania</wicri:regionArea><wicri:noRegion>Tasmania</wicri:noRegion></affiliation></author><author><name sortKey="Milne, Elizabeth" sort="Milne, Elizabeth" uniqKey="Milne E" first="Elizabeth" last="Milne">Elizabeth Milne</name><affiliation wicri:level="1"><nlm:aff id="au5"><institution>Telethon Kids Institute, University of Western Australia</institution><addr-line>Perth, Western Australia, Australia</addr-line></nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Perth, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation></author><author><name sortKey="Pedersen, Marie" sort="Pedersen, Marie" uniqKey="Pedersen M" first="Marie" last="Pedersen">Marie Pedersen</name><affiliation wicri:level="1"><nlm:aff id="au15"><institution>Centre for Research in Environmental Epidemiology (CREAL)</institution><addr-line>Barcelona, Spain</addr-line></nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea>Barcelona</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="au18"><institution>CIBER Epidemiología y Salud Pública (CIBERESP)</institution><addr-line>Madrid, Spain</addr-line></nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea>Madrid</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="au16"><institution>Universitat Pompeu Fabra</institution><addr-line>Barcelona, Spain</addr-line></nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea>Barcelona</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="au17"><institution>IMIM (Hospital del Mar Research Institute)</institution><addr-line>Barcelona, Spain</addr-line></nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea>Barcelona</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="au19"><institution>U823, Team of Environmental Epidemiology Applied to Reproduction and Respiratory Health, Institute Albert Bonniot, INSERM (National Institute of Health and Medical Research)</institution><addr-line>Grenoble, France</addr-line></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Grenoble</wicri:regionArea></affiliation></author><author><name sortKey="Kogevinas, Manolis" sort="Kogevinas, Manolis" uniqKey="Kogevinas M" first="Manolis" last="Kogevinas">Manolis Kogevinas</name><affiliation wicri:level="1"><nlm:aff id="au15"><institution>Centre for Research in Environmental Epidemiology (CREAL)</institution><addr-line>Barcelona, Spain</addr-line></nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea>Barcelona</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="au18"><institution>CIBER Epidemiología y Salud Pública (CIBERESP)</institution><addr-line>Madrid, Spain</addr-line></nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea>Madrid</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="au17"><institution>IMIM (Hospital del Mar Research Institute)</institution><addr-line>Barcelona, Spain</addr-line></nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea>Barcelona</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="au21"><institution>Department of Nutrition, National School of Public Health</institution><addr-line>Athens, Greece</addr-line></nlm:aff><country xml:lang="fr">Grèce</country><wicri:regionArea>Athens</wicri:regionArea></affiliation></author><author><name sortKey="Ha, Eunhee" sort="Ha, Eunhee" uniqKey="Ha E" first="Eunhee" last="Ha">Eunhee Ha</name><affiliation wicri:level="1"><nlm:aff id="au22"><institution>School of Medicine, Ewha Medical Research Center, Department of Preventive Medicine, Ewha Womans University</institution><addr-line>Seoul, Korea</addr-line></nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Seoul</wicri:regionArea></affiliation></author><author><name sortKey="Dwyer, Terence" sort="Dwyer, Terence" uniqKey="Dwyer T" first="Terence" last="Dwyer">Terence Dwyer</name><affiliation wicri:level="1"><nlm:aff id="au2"><institution>Department of Environmental and Genetic Epidemiology, Murdoch Children’s Research Institute, Royal Childrens Hospital, University of Melbourne</institution><addr-line>Melbourne, Australia</addr-line></nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Melbourne</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="au4"><institution>Menzies Research Institute, University of Tasmania</institution><addr-line>Hobart, Tasmania, Australia</addr-line></nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Hobart, Tasmania</wicri:regionArea><wicri:noRegion>Tasmania</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="au20"><institution>International Agency for Research on Cancer</institution><addr-line>Lyon, France</addr-line></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Lyon</wicri:regionArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">25989709</idno><idno type="pmc">4690513</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690513</idno><idno type="RBID">PMC:4690513</idno><idno type="doi">10.1111/ppe.12193</idno><date when="2015">2015</date><idno type="wicri:Area/Pmc/Corpus">000377</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000377</idno><idno type="wicri:Area/Pmc/Curation">000377</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000377</idno><idno type="wicri:Area/Pmc/Checkpoint">001150</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">001150</idno><idno type="wicri:source">PubMed</idno><idno type="wicri:Area/PubMed/Corpus">002B64</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">002B64</idno><idno type="wicri:Area/PubMed/Curation">002A92</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">002A92</idno><idno type="wicri:Area/PubMed/Checkpoint">002A92</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">002A92</idno><idno type="wicri:Area/Ncbi/Merge">002590</idno><idno type="wicri:Area/Ncbi/Curation">002590</idno><idno type="wicri:Area/Ncbi/Checkpoint">002590</idno><idno type="wicri:doubleKey">0269-5022:2015:Paltiel O:birthweight:and:childhood</idno><idno type="wicri:Area/Main/Merge">003108</idno><idno type="wicri:Area/Main/Curation">003107</idno><idno type="wicri:Area/Main/Exploration">003107</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Birthweight and Childhood Cancer: Preliminary Findings from the International Childhood Cancer Cohort Consortium (I4C)</title><author><name sortKey="Paltiel, Ora" sort="Paltiel, Ora" uniqKey="Paltiel O" first="Ora" last="Paltiel">Ora Paltiel</name><affiliation wicri:level="1"><nlm:aff id="au1"><institution>Department of Hematology, Braun School of Public Health, Hadassah-Hebrew University</institution><addr-line>Jerusalem, Israel</addr-line></nlm:aff><country xml:lang="fr">Israël</country><wicri:regionArea>Jerusalem</wicri:regionArea></affiliation></author><author><name sortKey="Tikellis, Gabriella" sort="Tikellis, Gabriella" uniqKey="Tikellis G" first="Gabriella" last="Tikellis">Gabriella Tikellis</name><affiliation wicri:level="1"><nlm:aff id="au2"><institution>Department of Environmental and Genetic Epidemiology, Murdoch Children’s Research Institute, Royal Childrens Hospital, University of Melbourne</institution><addr-line>Melbourne, Australia</addr-line></nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Melbourne</wicri:regionArea></affiliation></author><author><name sortKey="Linet, Martha" sort="Linet, Martha" uniqKey="Linet M" first="Martha" last="Linet">Martha Linet</name><affiliation wicri:level="1"><nlm:aff id="au6"><institution>Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health</institution><addr-line>Bethesda, MD, UK</addr-line></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Bethesda, MD</wicri:regionArea><wicri:noRegion>MD</wicri:noRegion></affiliation></author><author><name sortKey="Golding, Jean" sort="Golding, Jean" uniqKey="Golding J" first="Jean" last="Golding">Jean Golding</name><affiliation wicri:level="1"><nlm:aff id="au10"><institution>Centre for Child & Adolescent Health, School of Social & Community Medicine, University of Bristol</institution><addr-line>Bristol, UK</addr-line></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Bristol</wicri:regionArea></affiliation></author><author><name sortKey="Lemeshow, Stanley" sort="Lemeshow, Stanley" uniqKey="Lemeshow S" first="Stanley" last="Lemeshow">Stanley Lemeshow</name><affiliation wicri:level="1"><nlm:aff id="au7"><institution>Division of Biostatistics, College of Public Health, The Ohio State University</institution><addr-line>Columbus, Ohio, UK</addr-line></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Columbus, Ohio</wicri:regionArea><wicri:noRegion>Ohio</wicri:noRegion></affiliation></author><author><name sortKey="Phillips, Gary" sort="Phillips, Gary" uniqKey="Phillips G" first="Gary" last="Phillips">Gary Phillips</name><affiliation wicri:level="1"><nlm:aff id="au8"><institution>Division of Biostatistics, The Ohio State University Center for Biostatistics</institution><addr-line>Columbus, Ohio, UK</addr-line></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Columbus, Ohio</wicri:regionArea><wicri:noRegion>Ohio</wicri:noRegion></affiliation></author><author><name sortKey="Lamb, Karen" sort="Lamb, Karen" uniqKey="Lamb K" first="Karen" last="Lamb">Karen Lamb</name><affiliation wicri:level="1"><nlm:aff id="au3"><institution>Centre for Physical Activity and Nutrition, Deakin University</institution><addr-line>Burwood, Australia</addr-line></nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Burwood</wicri:regionArea></affiliation></author><author><name sortKey="Stoltenberg, Camilla" sort="Stoltenberg, Camilla" uniqKey="Stoltenberg C" first="Camilla" last="Stoltenberg">Camilla Stoltenberg</name><affiliation wicri:level="1"><nlm:aff id="au12"><institution>Norwegian Institute of Public Health</institution><addr-line>Oslo, Norway</addr-line></nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea>Oslo</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="au13"><institution>Department of Global Public Health and Community Care, University of Bergen</institution><addr-line>Bergen, Norway</addr-line></nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea>Bergen</wicri:regionArea></affiliation></author><author><name sortKey="H Berg, Siri E" sort="H Berg, Siri E" uniqKey="H Berg S" first="Siri E" last="H Berg">Siri E. H Berg</name><affiliation wicri:level="1"><nlm:aff id="au12"><institution>Norwegian Institute of Public Health</institution><addr-line>Oslo, Norway</addr-line></nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea>Oslo</wicri:regionArea></affiliation></author><author><name sortKey="Str M, Marin" sort="Str M, Marin" uniqKey="Str M M" first="Marin" last="Str M">Marin Str M</name><affiliation wicri:level="1"><nlm:aff id="au14"><institution>Department of Epidemiology Research, Center for Fetal Programming, Statenserum Institute</institution><addr-line>Copenhagen, Denmark</addr-line></nlm:aff><country xml:lang="fr">Danemark</country><wicri:regionArea>Copenhagen</wicri:regionArea></affiliation></author><author><name sortKey="Granstr M, Charlotta" sort="Granstr M, Charlotta" uniqKey="Granstr M C" first="Charlotta" last="Granstr M">Charlotta Granstr M</name><affiliation wicri:level="1"><nlm:aff id="au14"><institution>Department of Epidemiology Research, Center for Fetal Programming, Statenserum Institute</institution><addr-line>Copenhagen, Denmark</addr-line></nlm:aff><country xml:lang="fr">Danemark</country><wicri:regionArea>Copenhagen</wicri:regionArea></affiliation></author><author><name sortKey="Northstone, Kate" sort="Northstone, Kate" uniqKey="Northstone K" first="Kate" last="Northstone">Kate Northstone</name><affiliation wicri:level="1"><nlm:aff id="au11"><institution>ALSPAC (Children of the 90s), School of Social and Community Medicine, University of Bristol</institution><addr-line>Bristol, UK</addr-line></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Bristol</wicri:regionArea></affiliation></author><author><name sortKey="Klebanoff, Mark" sort="Klebanoff, Mark" uniqKey="Klebanoff M" first="Mark" last="Klebanoff">Mark Klebanoff</name><affiliation wicri:level="1"><nlm:aff id="au7"><institution>Division of Biostatistics, College of Public Health, The Ohio State University</institution><addr-line>Columbus, Ohio, UK</addr-line></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Columbus, Ohio</wicri:regionArea><wicri:noRegion>Ohio</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="au9"><institution>The Research Institute at Nationwide Children’s Hospital, The Ohio State University College of Medicine</institution><addr-line>Columbus, OH, UK</addr-line></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Columbus, OH</wicri:regionArea><wicri:noRegion>OH</wicri:noRegion></affiliation></author><author><name sortKey="Ponsonby, Anne Louise" sort="Ponsonby, Anne Louise" uniqKey="Ponsonby A" first="Anne-Louise" last="Ponsonby">Anne-Louise Ponsonby</name><affiliation wicri:level="1"><nlm:aff id="au2"><institution>Department of Environmental and Genetic Epidemiology, Murdoch Children’s Research Institute, Royal Childrens Hospital, University of Melbourne</institution><addr-line>Melbourne, Australia</addr-line></nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Melbourne</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="au4"><institution>Menzies Research Institute, University of Tasmania</institution><addr-line>Hobart, Tasmania, Australia</addr-line></nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Hobart, Tasmania</wicri:regionArea><wicri:noRegion>Tasmania</wicri:noRegion></affiliation></author><author><name sortKey="Milne, Elizabeth" sort="Milne, Elizabeth" uniqKey="Milne E" first="Elizabeth" last="Milne">Elizabeth Milne</name><affiliation wicri:level="1"><nlm:aff id="au5"><institution>Telethon Kids Institute, University of Western Australia</institution><addr-line>Perth, Western Australia, Australia</addr-line></nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Perth, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation></author><author><name sortKey="Pedersen, Marie" sort="Pedersen, Marie" uniqKey="Pedersen M" first="Marie" last="Pedersen">Marie Pedersen</name><affiliation wicri:level="1"><nlm:aff id="au15"><institution>Centre for Research in Environmental Epidemiology (CREAL)</institution><addr-line>Barcelona, Spain</addr-line></nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea>Barcelona</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="au18"><institution>CIBER Epidemiología y Salud Pública (CIBERESP)</institution><addr-line>Madrid, Spain</addr-line></nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea>Madrid</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="au16"><institution>Universitat Pompeu Fabra</institution><addr-line>Barcelona, Spain</addr-line></nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea>Barcelona</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="au17"><institution>IMIM (Hospital del Mar Research Institute)</institution><addr-line>Barcelona, Spain</addr-line></nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea>Barcelona</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="au19"><institution>U823, Team of Environmental Epidemiology Applied to Reproduction and Respiratory Health, Institute Albert Bonniot, INSERM (National Institute of Health and Medical Research)</institution><addr-line>Grenoble, France</addr-line></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Grenoble</wicri:regionArea></affiliation></author><author><name sortKey="Kogevinas, Manolis" sort="Kogevinas, Manolis" uniqKey="Kogevinas M" first="Manolis" last="Kogevinas">Manolis Kogevinas</name><affiliation wicri:level="1"><nlm:aff id="au15"><institution>Centre for Research in Environmental Epidemiology (CREAL)</institution><addr-line>Barcelona, Spain</addr-line></nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea>Barcelona</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="au18"><institution>CIBER Epidemiología y Salud Pública (CIBERESP)</institution><addr-line>Madrid, Spain</addr-line></nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea>Madrid</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="au17"><institution>IMIM (Hospital del Mar Research Institute)</institution><addr-line>Barcelona, Spain</addr-line></nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea>Barcelona</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="au21"><institution>Department of Nutrition, National School of Public Health</institution><addr-line>Athens, Greece</addr-line></nlm:aff><country xml:lang="fr">Grèce</country><wicri:regionArea>Athens</wicri:regionArea></affiliation></author><author><name sortKey="Ha, Eunhee" sort="Ha, Eunhee" uniqKey="Ha E" first="Eunhee" last="Ha">Eunhee Ha</name><affiliation wicri:level="1"><nlm:aff id="au22"><institution>School of Medicine, Ewha Medical Research Center, Department of Preventive Medicine, Ewha Womans University</institution><addr-line>Seoul, Korea</addr-line></nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Seoul</wicri:regionArea></affiliation></author><author><name sortKey="Dwyer, Terence" sort="Dwyer, Terence" uniqKey="Dwyer T" first="Terence" last="Dwyer">Terence Dwyer</name><affiliation wicri:level="1"><nlm:aff id="au2"><institution>Department of Environmental and Genetic Epidemiology, Murdoch Children’s Research Institute, Royal Childrens Hospital, University of Melbourne</institution><addr-line>Melbourne, Australia</addr-line></nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Melbourne</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="au4"><institution>Menzies Research Institute, University of Tasmania</institution><addr-line>Hobart, Tasmania, Australia</addr-line></nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Hobart, Tasmania</wicri:regionArea><wicri:noRegion>Tasmania</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="au20"><institution>International Agency for Research on Cancer</institution><addr-line>Lyon, France</addr-line></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Lyon</wicri:regionArea></affiliation></author></analytic><series><title level="j">Paediatric and Perinatal Epidemiology</title><idno type="ISSN">0269-5022</idno><idno type="eISSN">1365-3016</idno><imprint><date when="2015">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term><term>Age of Onset</term><term>Australia (epidemiology)</term><term>Birth Weight</term><term>Child</term><term>Child, Preschool</term><term>Denmark (epidemiology)</term><term>Female</term><term>Humans</term><term>Infant</term><term>Infant, Newborn</term><term>Israel (epidemiology)</term><term>Male</term><term>Neoplasms (epidemiology)</term><term>Neoplasms (etiology)</term><term>Norway (epidemiology)</term><term>Odds Ratio</term><term>Risk Factors</term><term>United Kingdom (epidemiology)</term><term>United States (epidemiology)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adolescent</term><term>Australie (épidémiologie)</term><term>Danemark (épidémiologie)</term><term>Enfant</term><term>Enfant d'âge préscolaire</term><term>Facteurs de risque</term><term>Femelle</term><term>Humains</term><term>Israël (épidémiologie)</term><term>Mâle</term><term>Norvège (épidémiologie)</term><term>Nourrisson</term><term>Nouveau-né</term><term>Odds ratio</term><term>Poids de naissance</term><term>Royaume-Uni (épidémiologie)</term><term>Tumeurs (épidémiologie)</term><term>Tumeurs (étiologie)</term><term>Âge de début</term><term>États-Unis d'Amérique (épidémiologie)</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Australia</term><term>Denmark</term><term>Israel</term><term>Neoplasms</term><term>Norway</term><term>United Kingdom</term><term>United States</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Neoplasms</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Australie</term><term>Danemark</term><term>Israël</term><term>Norvège</term><term>Royaume-Uni</term><term>Tumeurs</term><term>États-Unis d'Amérique</term></keywords><keywords scheme="MESH" qualifier="étiologie" xml:lang="fr"><term>Tumeurs</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adolescent</term><term>Age of Onset</term><term>Birth Weight</term><term>Child</term><term>Child, Preschool</term><term>Female</term><term>Humans</term><term>Infant</term><term>Infant, Newborn</term><term>Male</term><term>Odds Ratio</term><term>Risk Factors</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adolescent</term><term>Enfant</term><term>Enfant d'âge préscolaire</term><term>Facteurs de risque</term><term>Femelle</term><term>Humains</term><term>Mâle</term><term>Nourrisson</term><term>Nouveau-né</term><term>Odds ratio</term><term>Poids de naissance</term><term>Âge de début</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec><title>Background</title><p>Evidence relating childhood cancer to high birthweight is derived primarily from registry and case–control studies. We aimed to investigate this association, exploring the potential modifying roles of age at diagnosis and maternal anthropometrics, using prospectively collected data from the International Childhood Cancer Cohort Consortium.</p></sec><sec><title>Methods</title><p>We pooled data on infant and parental characteristics and cancer incidence from six geographically and temporally diverse member cohorts [the Avon Longitudinal Study of Parents and Children (UK), the Collaborative Perinatal Project (USA), the Danish National Birth Cohort (Denmark), the Jerusalem Perinatal Study (Israel), the Norwegian Mother and Child Cohort Study (Norway), and the Tasmanian Infant Health Survey (Australia)]. Birthweight metrics included a continuous measure, deciles, and categories (≥4.0 vs. <4.0 kilogram). Childhood cancer (377 cases diagnosed prior to age 15 years) risk was analysed by type (all sites, leukaemia, acute lymphoblastic leukaemia, and non-leukaemia) and age at diagnosis. We estimated hazard ratios (HR) and 95% confidence intervals (CI) from Cox proportional hazards models stratified by cohort.</p></sec><sec><title>Results</title><p>A linear relationship was noted for each kilogram increment in birthweight adjusted for gender and gestational age for all cancers [HR = 1.26; 95% CI 1.02, 1.54]. Similar trends were observed for leukaemia. There were no significant interactions with maternal pre-pregnancy overweight or pregnancy weight gain. Birthweight ≥4.0 kg was associated with non-leukaemia cancer among children diagnosed at age ≥3 years [HR = 1.62; 95% CI 1.06, 2.46], but not at younger ages [HR = 0.7; 95% CI 0.45, 1.24, <italic>P</italic> for difference = 0.02].</p></sec><sec><title>Conclusion</title><p>Childhood cancer incidence rises with increasing birthweight. In older children, cancers other than leukaemia are particularly related to high birthweight. Maternal adiposity, currently widespread, was not demonstrated to substantially modify these associations. Common factors underlying foetal growth and carcinogenesis need to be further explored.</p></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Macmahon, B" uniqKey="Macmahon B">B MacMahon</name></author><author><name sortKey="Newill, Va" uniqKey="Newill V">VA Newill</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Iverson, T" uniqKey="Iverson T">T Iverson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jackson, Ew" uniqKey="Jackson E">EW Jackson</name></author><author><name sortKey="Norris, Fd" uniqKey="Norris F">FD Norris</name></author><author><name sortKey="Klauber, Mr" uniqKey="Klauber M">MR Klauber</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hjalgrim, Ll" uniqKey="Hjalgrim L">LL Hjalgrim</name></author><author><name sortKey="Rostgaard, K" uniqKey="Rostgaard K">K Rostgaard</name></author><author><name sortKey="Hjalgrim, H" uniqKey="Hjalgrim H">H Hjalgrim</name></author><author><name sortKey="Westergaard, T" uniqKey="Westergaard T">T Westergaard</name></author><author><name sortKey="Thomassen, H" uniqKey="Thomassen H">H Thomassen</name></author><author><name sortKey="Forestier, E" uniqKey="Forestier E">E Forestier</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Caughey, Rw" uniqKey="Caughey R">RW Caughey</name></author><author><name sortKey="Michels, Kb" uniqKey="Michels K">KB Michels</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Glinianaia, Sv" uniqKey="Glinianaia S">SV Glinianaia</name></author><author><name sortKey="Pearce, Ms" uniqKey="Pearce M">MS Pearce</name></author><author><name sortKey="Rankin, J" uniqKey="Rankin J">J Rankin</name></author><author><name sortKey="Pless Mulloli, T" uniqKey="Pless Mulloli T">T Pless-Mulloli</name></author><author><name sortKey="Parker, L" uniqKey="Parker L">L Parker</name></author><author><name sortKey="Mcnally, Rj" uniqKey="Mcnally R">RJ McNally</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shaw, G" uniqKey="Shaw G">G Shaw</name></author><author><name sortKey="Lavey, R" uniqKey="Lavey R">R Lavey</name></author><author><name sortKey="Jackson, R" uniqKey="Jackson R">R Jackson</name></author><author><name sortKey="Austin, D" uniqKey="Austin D">D Austin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mckinney, Pa" uniqKey="Mckinney P">PA McKinney</name></author><author><name sortKey="Cartwright, Ra" uniqKey="Cartwright R">RA Cartwright</name></author><author><name sortKey="Saiu, Jm" uniqKey="Saiu J">JM Saiu</name></author><author><name sortKey="Mann, Jr" uniqKey="Mann J">JR Mann</name></author><author><name sortKey="Stiller, Ca" uniqKey="Stiller C">CA Stiller</name></author><author><name sortKey="Draper, Gj" uniqKey="Draper G">GJ Draper</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bjorge, T" uniqKey="Bjorge T">T Bjorge</name></author><author><name sortKey="Sorensen, Ht" uniqKey="Sorensen H">HT Sorensen</name></author><author><name sortKey="Grotmol, T" uniqKey="Grotmol T">T Grotmol</name></author><author><name sortKey="Engeland, A" uniqKey="Engeland A">A Engeland</name></author><author><name sortKey="Stephansson, O" uniqKey="Stephansson O">O Stephansson</name></author><author><name sortKey="Gissler, M" uniqKey="Gissler M">M Gissler</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Schmidt, Ls" uniqKey="Schmidt L">LS Schmidt</name></author><author><name sortKey="Schuz, J" uniqKey="Schuz J">J Schuz</name></author><author><name sortKey="Lahteenmaki, P" uniqKey="Lahteenmaki P">P Lahteenmaki</name></author><author><name sortKey="Trager, C" uniqKey="Trager C">C Trager</name></author><author><name sortKey="Stokland, T" uniqKey="Stokland T">T Stokland</name></author><author><name sortKey="Gustafson, G" uniqKey="Gustafson G">G Gustafson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="O Eill, Ka" uniqKey="O Eill K">KA O’Neill</name></author><author><name sortKey="Murphy, Mfg" uniqKey="Murphy M">MFG Murphy</name></author><author><name sortKey="Bunch, Kj" uniqKey="Bunch K">KJ Bunch</name></author><author><name sortKey="Puumala, Se" uniqKey="Puumala S">SE Puumala</name></author><author><name sortKey="Carozza, Se" uniqKey="Carozza S">SE Carozza</name></author><author><name sortKey="Chow, Ej" uniqKey="Chow E">EJ Chow</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Milne, E" uniqKey="Milne E">E Milne</name></author><author><name sortKey="Laurvick, Cl" uniqKey="Laurvick C">CL Laurvick</name></author><author><name sortKey="Blair, E" uniqKey="Blair E">E Blair</name></author><author><name sortKey="Bower, C" uniqKey="Bower C">C Bower</name></author><author><name sortKey="De Klerk, N" uniqKey="De Klerk N">N de Klerk</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sprehe, Mr" uniqKey="Sprehe M">MR Sprehe</name></author><author><name sortKey="Barahmani, N" uniqKey="Barahmani N">N Barahmani</name></author><author><name sortKey="Cao, Y" uniqKey="Cao Y">Y Cao</name></author><author><name sortKey="Wang, T" uniqKey="Wang T">T Wang</name></author><author><name sortKey="Forman, Mr" uniqKey="Forman M">MR Forman</name></author><author><name sortKey="Bondy, M" uniqKey="Bondy M">M Bondy</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Samuelsen, So" uniqKey="Samuelsen S">SO Samuelsen</name></author><author><name sortKey="Bakketeig, Ls" uniqKey="Bakketeig L">LS Bakketeig</name></author><author><name sortKey="Tretli, S" uniqKey="Tretli S">S Tretli</name></author><author><name sortKey="Johannesen, Tb" uniqKey="Johannesen T">TB Johannesen</name></author><author><name sortKey="Magnus, P" uniqKey="Magnus P">P Magnus</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rangel, M" uniqKey="Rangel M">M Rangel</name></author><author><name sortKey="Cypriano, M" uniqKey="Cypriano M">M Cypriano</name></author><author><name sortKey="De Martino Lee, Ml" uniqKey="De Martino Lee M">ML de Martino Lee</name></author><author><name sortKey="Luisi, Fa" uniqKey="Luisi F">FA Luisi</name></author><author><name sortKey="Petrilli, As" uniqKey="Petrilli A">AS Petrilli</name></author><author><name sortKey="Strufaldi, Mw" uniqKey="Strufaldi M">MW Strufaldi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Schuz, J" uniqKey="Schuz J">J Schuz</name></author><author><name sortKey="Forman, Mr" uniqKey="Forman M">MR Forman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Milne, E" uniqKey="Milne E">E Milne</name></author><author><name sortKey="Greenop, Kr" uniqKey="Greenop K">KR Greenop</name></author><author><name sortKey="Metayer, C" uniqKey="Metayer C">C Metayer</name></author><author><name sortKey="Schuz, J" uniqKey="Schuz J">J Schuz</name></author><author><name sortKey="Petridou, E" uniqKey="Petridou E">E Petridou</name></author><author><name sortKey="Pombo De Oliveira, Ms" uniqKey="Pombo De Oliveira M">MS Pombo-de-Oliveira</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Roman, E" uniqKey="Roman E">E Roman</name></author><author><name sortKey="Lightfoot, T" uniqKey="Lightfoot T">T Lightfoot</name></author><author><name sortKey="Smith, Ag" uniqKey="Smith A">AG Smith</name></author><author><name sortKey="Forman, Mr" uniqKey="Forman M">MR Forman</name></author><author><name sortKey="Linet, Ms" uniqKey="Linet M">MS Linet</name></author><author><name sortKey="Robison, L" uniqKey="Robison L">L Robison</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Johnston, Lb" uniqKey="Johnston L">LB Johnston</name></author><author><name sortKey="Clark, Aj" uniqKey="Clark A">AJ Clark</name></author><author><name sortKey="Savage, Mo" uniqKey="Savage M">MO Savage</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Amini, Sb" uniqKey="Amini S">SB Amini</name></author><author><name sortKey="Catalano, Pm" uniqKey="Catalano P">PM Catalano</name></author><author><name sortKey="Hirsch, V" uniqKey="Hirsch V">V Hirsch</name></author><author><name sortKey="Mann, Li" uniqKey="Mann L">LI Mann</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dubois, L" uniqKey="Dubois L">L Dubois</name></author><author><name sortKey="Girard, M" uniqKey="Girard M">M Girard</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bhattacharya, S" uniqKey="Bhattacharya S">S Bhattacharya</name></author><author><name sortKey="Campbell, Dm" uniqKey="Campbell D">DM Campbell</name></author><author><name sortKey="Liston, Wa" uniqKey="Liston W">WA Liston</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nohr, Ea" uniqKey="Nohr E">EA Nohr</name></author><author><name sortKey="Vaeth, M" uniqKey="Vaeth M">M Vaeth</name></author><author><name sortKey="Baker, Jl" uniqKey="Baker J">JL Baker</name></author><author><name sortKey="Sorensen, T" uniqKey="Sorensen T">T Sorensen</name></author><author><name sortKey="Olsen, J" uniqKey="Olsen J">J Olsen</name></author><author><name sortKey="Rasmussen, Km" uniqKey="Rasmussen K">KM Rasmussen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lu, Gc" uniqKey="Lu G">GC Lu</name></author><author><name sortKey="Rouse, Dj" uniqKey="Rouse D">DJ Rouse</name></author><author><name sortKey="Dubard, M" uniqKey="Dubard M">M DuBard</name></author><author><name sortKey="Cliver, S" uniqKey="Cliver S">S Cliver</name></author><author><name sortKey="Kimberlin, D" uniqKey="Kimberlin D">D Kimberlin</name></author><author><name sortKey="Hauth, Jc" uniqKey="Hauth J">JC Hauth</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hochner, H" uniqKey="Hochner H">H Hochner</name></author><author><name sortKey="Friedlander, Y" uniqKey="Friedlander Y">Y Friedlander</name></author><author><name sortKey="Calderon Margalit, R" uniqKey="Calderon Margalit R">R Calderon-Margalit</name></author><author><name sortKey="Meiner, V" uniqKey="Meiner V">V Meiner</name></author><author><name sortKey="Sagy, Y" uniqKey="Sagy Y">Y Sagy</name></author><author><name sortKey="Avgil Tsadok, M" uniqKey="Avgil Tsadok M">M Avgil-Tsadok</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mclaughlin, Cc" uniqKey="Mclaughlin C">CC McLaughlin</name></author><author><name sortKey="Baptiste, Ms" uniqKey="Baptiste M">MS Baptiste</name></author><author><name sortKey="Schymura, Mj" uniqKey="Schymura M">MJ Schymura</name></author><author><name sortKey="Nasca, Pc" uniqKey="Nasca P">PC Nasca</name></author><author><name sortKey="Zdeb, Ms" uniqKey="Zdeb M">MS Zdeb</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Brown, Rc" uniqKey="Brown R">RC Brown</name></author><author><name sortKey="Dwyer, T" uniqKey="Dwyer T">T Dwyer</name></author><author><name sortKey="Kasten, C" uniqKey="Kasten C">C Kasten</name></author><author><name sortKey="Krotoski, D" uniqKey="Krotoski D">D Krotoski</name></author><author><name sortKey="Li, Z" uniqKey="Li Z">Z Li</name></author><author><name sortKey="Linet, Ms" uniqKey="Linet M">MS Linet</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Vogel, Jp" uniqKey="Vogel J">JP Vogel</name></author><author><name sortKey="Torloni, Mr" uniqKey="Torloni M">MR Torloni</name></author><author><name sortKey="Seuc, A" uniqKey="Seuc A">A Seuc</name></author><author><name sortKey="Betran, Ap" uniqKey="Betran A">AP Betran</name></author><author><name sortKey="Widmer, M" uniqKey="Widmer M">M Widmer</name></author><author><name sortKey="Souza, Jp" uniqKey="Souza J">JP Souza</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Seewald, L" uniqKey="Seewald L">L Seewald</name></author><author><name sortKey="Taub, Jw" uniqKey="Taub J">JW Taub</name></author><author><name sortKey="Maloney, Kw" uniqKey="Maloney K">KW Maloney</name></author><author><name sortKey="Mccabe, Er" uniqKey="Mccabe E">ER McCabe</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fritz, A" uniqKey="Fritz A">A Fritz</name></author><author><name sortKey="Percy, C" uniqKey="Percy C">C Percy</name></author><author><name sortKey="Jack, A" uniqKey="Jack A">A Jack</name></author><author><name sortKey="Shanmugaratnam, K" uniqKey="Shanmugaratnam K">K Shanmugaratnam</name></author><author><name sortKey="Sobin, L" uniqKey="Sobin L">L Sobin</name></author><author><name sortKey="Parkin, M" uniqKey="Parkin M">M Parkin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="White, Ir" uniqKey="White I">IR White</name></author><author><name sortKey="Royston, P" uniqKey="Royston P">P Royston</name></author><author><name sortKey="Wood, Am" uniqKey="Wood A">AM Wood</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Grambsch, Pm" uniqKey="Grambsch P">PM Grambsch</name></author><author><name sortKey="Therneau, Tm" uniqKey="Therneau T">TM Therneau</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Royston, P" uniqKey="Royston P">P Royston</name></author><author><name sortKey="Altman, Dg" uniqKey="Altman D">DG Altman</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Rasmussen, Km" uniqKey="Rasmussen K">KM Rasmussen</name></author><author><name sortKey="Catalano, Pm" uniqKey="Catalano P">PM Catalano</name></author><author><name sortKey="Yatkine, Al" uniqKey="Yatkine A">AL Yatkine</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lee, J" uniqKey="Lee J">J Lee</name></author><author><name sortKey="Chia, Ks" uniqKey="Chia K">KS Chia</name></author><author><name sortKey="Cheung, Kh" uniqKey="Cheung K">KH Cheung</name></author><author><name sortKey="Chia, Se" uniqKey="Chia S">SE Chia</name></author><author><name sortKey="Lee, Hp" uniqKey="Lee H">HP Lee</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Westergaard, T" uniqKey="Westergaard T">T Westergaard</name></author><author><name sortKey="Andersen, Pk" uniqKey="Andersen P">PK Andersen</name></author><author><name sortKey="Pedersen, Jb" uniqKey="Pedersen J">JB Pedersen</name></author><author><name sortKey="Olsen, Jh" uniqKey="Olsen J">JH Olsen</name></author><author><name sortKey="Frisch, M" uniqKey="Frisch M">M Frisch</name></author><author><name sortKey="Sorensen, Ht" uniqKey="Sorensen H">HT Sorensen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rees, M" uniqKey="Rees M">M Rees</name></author><author><name sortKey="Karoshi, Ma" uniqKey="Karoshi M">MA Karoshi</name></author><author><name sortKey="Keith, L" uniqKey="Keith L">L Keith</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chokkalingam, Ap" uniqKey="Chokkalingam A">AP Chokkalingam</name></author><author><name sortKey="Metayer, C" uniqKey="Metayer C">C Metayer</name></author><author><name sortKey="Scelo, G" uniqKey="Scelo G">G Scelo</name></author><author><name sortKey="Chang, Js" uniqKey="Chang J">JS Chang</name></author><author><name sortKey="Schiffman, J" uniqKey="Schiffman J">J Schiffman</name></author><author><name sortKey="Urayama, Ky" uniqKey="Urayama K">KY Urayama</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chu, A" uniqKey="Chu A">A Chu</name></author><author><name sortKey="Heck, Je" uniqKey="Heck J">JE Heck</name></author><author><name sortKey="Ribeiro, Kb" uniqKey="Ribeiro K">KB Ribeiro</name></author><author><name sortKey="Brennan, P" uniqKey="Brennan P">P Brennan</name></author><author><name sortKey="Boffetta, P" uniqKey="Boffetta P">P Boffetta</name></author><author><name sortKey="Buffler, P" uniqKey="Buffler P">P Buffler</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Puumala, Se" uniqKey="Puumala S">SE Puumala</name></author><author><name sortKey="Spector, Lg" uniqKey="Spector L">LG Spector</name></author><author><name sortKey="Robison, Ll" uniqKey="Robison L">LL Robison</name></author><author><name sortKey="Bunin, Gr" uniqKey="Bunin G">GR Bunin</name></author><author><name sortKey="Olshan, Af" uniqKey="Olshan A">AF Olshan</name></author><author><name sortKey="Linabery, Am" uniqKey="Linabery A">AM Linabery</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Australie</li><li>Corée du Sud</li><li>Danemark</li><li>Espagne</li><li>France</li><li>Grèce</li><li>Israël</li><li>Norvège</li><li>Royaume-Uni</li></country></list><tree><country name="Israël"><noRegion><name sortKey="Paltiel, Ora" sort="Paltiel, Ora" uniqKey="Paltiel O" first="Ora" last="Paltiel">Ora Paltiel</name></noRegion></country><country name="Australie"><noRegion><name sortKey="Tikellis, Gabriella" sort="Tikellis, Gabriella" uniqKey="Tikellis G" first="Gabriella" last="Tikellis">Gabriella Tikellis</name></noRegion><name sortKey="Dwyer, Terence" sort="Dwyer, Terence" uniqKey="Dwyer T" first="Terence" last="Dwyer">Terence Dwyer</name><name sortKey="Dwyer, Terence" sort="Dwyer, Terence" uniqKey="Dwyer T" first="Terence" last="Dwyer">Terence Dwyer</name><name sortKey="Lamb, Karen" sort="Lamb, Karen" uniqKey="Lamb K" first="Karen" last="Lamb">Karen Lamb</name><name sortKey="Milne, Elizabeth" sort="Milne, Elizabeth" uniqKey="Milne E" first="Elizabeth" last="Milne">Elizabeth Milne</name><name sortKey="Ponsonby, Anne Louise" sort="Ponsonby, Anne Louise" uniqKey="Ponsonby A" first="Anne-Louise" last="Ponsonby">Anne-Louise Ponsonby</name><name sortKey="Ponsonby, Anne Louise" sort="Ponsonby, Anne Louise" uniqKey="Ponsonby A" first="Anne-Louise" last="Ponsonby">Anne-Louise Ponsonby</name></country><country name="Royaume-Uni"><noRegion><name sortKey="Linet, Martha" sort="Linet, Martha" uniqKey="Linet M" first="Martha" last="Linet">Martha Linet</name></noRegion><name sortKey="Golding, Jean" sort="Golding, Jean" uniqKey="Golding J" first="Jean" last="Golding">Jean Golding</name><name sortKey="Klebanoff, Mark" sort="Klebanoff, Mark" uniqKey="Klebanoff M" first="Mark" last="Klebanoff">Mark Klebanoff</name><name sortKey="Klebanoff, Mark" sort="Klebanoff, Mark" uniqKey="Klebanoff M" first="Mark" last="Klebanoff">Mark Klebanoff</name><name sortKey="Lemeshow, Stanley" sort="Lemeshow, Stanley" uniqKey="Lemeshow S" first="Stanley" last="Lemeshow">Stanley Lemeshow</name><name sortKey="Northstone, Kate" sort="Northstone, Kate" uniqKey="Northstone K" first="Kate" last="Northstone">Kate Northstone</name><name sortKey="Phillips, Gary" sort="Phillips, Gary" uniqKey="Phillips G" first="Gary" last="Phillips">Gary Phillips</name></country><country name="Norvège"><noRegion><name sortKey="Stoltenberg, Camilla" sort="Stoltenberg, Camilla" uniqKey="Stoltenberg C" first="Camilla" last="Stoltenberg">Camilla Stoltenberg</name></noRegion><name sortKey="H Berg, Siri E" sort="H Berg, Siri E" uniqKey="H Berg S" first="Siri E" last="H Berg">Siri E. H Berg</name><name sortKey="Stoltenberg, Camilla" sort="Stoltenberg, Camilla" uniqKey="Stoltenberg C" first="Camilla" last="Stoltenberg">Camilla Stoltenberg</name></country><country name="Danemark"><noRegion><name sortKey="Str M, Marin" sort="Str M, Marin" uniqKey="Str M M" first="Marin" last="Str M">Marin Str M</name></noRegion><name sortKey="Granstr M, Charlotta" sort="Granstr M, Charlotta" uniqKey="Granstr M C" first="Charlotta" last="Granstr M">Charlotta Granstr M</name></country><country name="Espagne"><noRegion><name sortKey="Pedersen, Marie" sort="Pedersen, Marie" uniqKey="Pedersen M" first="Marie" last="Pedersen">Marie Pedersen</name></noRegion><name sortKey="Kogevinas, Manolis" sort="Kogevinas, Manolis" uniqKey="Kogevinas M" first="Manolis" last="Kogevinas">Manolis Kogevinas</name><name sortKey="Kogevinas, Manolis" sort="Kogevinas, Manolis" uniqKey="Kogevinas M" first="Manolis" last="Kogevinas">Manolis Kogevinas</name><name sortKey="Kogevinas, Manolis" sort="Kogevinas, Manolis" uniqKey="Kogevinas M" first="Manolis" last="Kogevinas">Manolis Kogevinas</name><name sortKey="Pedersen, Marie" sort="Pedersen, Marie" uniqKey="Pedersen M" first="Marie" last="Pedersen">Marie Pedersen</name><name sortKey="Pedersen, Marie" sort="Pedersen, Marie" uniqKey="Pedersen M" first="Marie" last="Pedersen">Marie Pedersen</name><name sortKey="Pedersen, Marie" sort="Pedersen, Marie" uniqKey="Pedersen M" first="Marie" last="Pedersen">Marie Pedersen</name></country><country name="France"><noRegion><name sortKey="Pedersen, Marie" sort="Pedersen, Marie" uniqKey="Pedersen M" first="Marie" last="Pedersen">Marie Pedersen</name></noRegion><name sortKey="Dwyer, Terence" sort="Dwyer, Terence" uniqKey="Dwyer T" first="Terence" last="Dwyer">Terence Dwyer</name></country><country name="Grèce"><noRegion><name sortKey="Kogevinas, Manolis" sort="Kogevinas, Manolis" uniqKey="Kogevinas M" first="Manolis" last="Kogevinas">Manolis Kogevinas</name></noRegion></country><country name="Corée du Sud"><noRegion><name sortKey="Ha, Eunhee" sort="Ha, Eunhee" uniqKey="Ha E" first="Eunhee" last="Ha">Eunhee Ha</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Asie/explor/AustralieFrV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 003107 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 003107 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Asie
|area= AustralieFrV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= PMC:4690513
|texte= Birthweight and Childhood Cancer: Preliminary Findings from the International Childhood Cancer Cohort Consortium (I4C)
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:25989709" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a AustralieFrV1
| This area was generated with Dilib version V0.6.33. |  |